| 名稱 | AI-Edigene® BRAF p.V600R Reference Standard P |
| 型號 | CBP10426 |
| 報價 |  |
| 特點 | AI-Edigene® BRAF p.V600R Reference Standard Plus |
產品搜索
相關文章
聯系我們
產品展示 / PRODUCTS
- 詳細內容
CBP10426 | |
| Format | Genomic DNA |
| Description | BRAF, serine/threonine-protein kinase B-raf, is a member of the Raf family of serine/threonine protein kinases, which signals through the MAP kinase pathway to regulate cell proliferation and cell growth (PMID: 24737949, PMID: 29540830). BRAF mutations have been identified in a variety of cancers, including, colorectal (PMID: 30122982), lung (PMID: 29729495), thyroid (PMID: 12970315), and melanoma (PMID: 24737949), and a number of mutations have also been demonstrated to confer drug resistance (PMID: 27478040). |
| Technical Data | |
| DNA Change | c.1798_1799GT>AG |
| AA Change | p.V600R |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000288602 |
| Cosmic ID | COSM474 |
| Chr position(GRCh37) | chr7:140453136_140453137 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
