| 名稱 | AI-Edigene® FLT3 p.I836del Reference Standard |
| 型號(hào) | CBP10525 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | AI-Edigene® FLT3 p.I836del Reference Standard Plus |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10525AI-Edigene® FLT3 p.I836del Reference Standard
- 詳細(xì)內(nèi)容
CBP10525 | |
| Format | Genomic DNA |
| Description | FLT3 I836del results in the deletion of an amino acid in the protein kinase domain activation loop of the Flt3 protein at amino acid 836 (PMID: 12663439). I836del results in constitutive phosphorylation of Flt3 and activation of Stat5, Erk signaling, leading to transformation of cultured cells (PMID: 15256420). |
| Technical Data | |
| DNA Change | c.2508_2510delCAT |
| AA Change | p.I836del |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | NM_004119.3 |
| Cosmic ID | COSM797 |
| Chr position(GRCh37) | chr13:28592637_28592639 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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