| 名稱 | BRAF p.K601N Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10237 |
| 報價 | 900 |
| 特點(diǎn) | BRAF p.K601N Reference Standard |
產(chǎn)品搜索
相關(guān)文章
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： [email protected]
電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： [email protected]
產(chǎn)品展示 / PRODUCTS
基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10237BRAF p.K601N Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10237 | |
| Format | Genomic DNA |
| Description | BRAF K601N lies within the protein kinase domain of the Braf protein (UniProt.org). K601N confers a gain of function on Braf, as indicated by increased phosphorylation of MEK and ERK in cell in culture (PMID: 24434212) and induction of cell proliferation and cell viability in culture (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.1803A>T |
| AA Change | p.K601N |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000288602 |
| Cosmic ID | COSM6265 |
| Chr position(GRCh37) | chr7:140453132 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
