基因檢測標準品 > Mutation > CBP10241BRAF p.L597V Reference Standard 標準品
名稱
BRAF p.L597V Reference Standard 標準品
型號
CBP10241
報價
900
特點
BRAF p.L597V Reference Standard
詳細內(nèi)容
CBP10241
Format
Genomic DNA
Description
BRAF L597V lies within the protein kinase domain of the Braf protein (UniProt.org). L597V results in activation of Braf as indicated by increased phosphorylation of Mek and Erk in cell culture (PMID: 22798288) and and induces cell proliferation and cell viability in culture (PMID: 29533785).
Technical Data
DNA Change
c.1789C>G
AA Change
p.L597V
Mutation type
Substitution - Missense
Zygosity
Heterozygous
Allelic Frequency
33.33%
Transcript
ENST00000288602
Cosmic ID
COSM470
Chr position(GRCh37)
chr7:140453146
Buffer
Tris-EDTA
Product Information
Intended Use
Research Use Only
Unit Size
1ug
Concentration
Download for COA
Purofication
Download for COA
DNA electrophoresis
Download for COA
Sanger sequencing
Storage
4℃
Expiry
36 months from the date of manufacture
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