| 名稱 | BRCA2 p.F1427fs Reference Standard 標準品 |
| 型號 | CBP10454 |
| 報價 |  |
| 特點 | BRCA2 p.F1427fs Reference Standard |
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- 詳細內容
CBP10454 | |
| Gene | BRCA2 |
| Description | BRCA2, breast cancer type 2 susceptibility protein, is a tumor suppressor involved in the homologous recombination pathway for double-strand DNA repair, thereby playing a role in genome stability (PMID: 27530658). BRCA2 germline mutations increase the risk of developing ovarian and/or breast cancer (PMID: 23364291) and somatic mutations are highest in colon, NSCLC, and ovarian cancers (PMID: 27283171). |
| Technical Data | |
| DNA Change | c.4277_4278insT |
| AA Change | p.F1427fs |
| Mutation type | Frame_Shift_Ins |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000380152.3 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr13:32912770_32912771 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
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| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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