基因檢測標準品 > Mutation > CBP10496MAP2K1 p.Q56P Reference Standard 標準品
名稱
MAP2K1 p.Q56P Reference Standard 標準品
型號
CBP10496
報價
900
特點
MAP2K1 p.Q56P Reference Standard
詳細內容
CBP10496
Format
Genomic DNA
Description
MAP2K1 Q56P does not lie within any known functional domains of the Map2k1 protein (UniProt.org). Q56P confers a gain of function to the Map2k1 protein as indicated by increased kinase activity and the ability to transform cultured cells (PMID: 22327936, PMID: 7651428) and also demonstrates resistance to some Mek and Braf inhibitors (PMID: 29753091).
Technical Data
DNA Change
c.167A>C
AA Change
p.Q56P
Mutation type
Substitution - Missense
Zygosity
Heterozygous
Allelic Frequency
50.00%
Transcript
ENST00000307102.9
Cosmic ID
COSM1235481
Chr position(GRCh37)
chr15:66727451
Buffer
Tris-EDTA
Product Information
Intended Use
Research Use Only
Unit Size
1ug
Concentration
Download for COA
Purofication
Download for COA
DNA electrophoresis
Download for COA
Sanger sequencing
Storage
4℃
Expiry
36 months from the date of manufacture
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