基因檢測標準品 > Mutation > CBP10543PIK3CA p.E545G Reference Standard 標準品
名稱
PIK3CA p.E545G Reference Standard 標準品
型號
CBP10543
報價
特點
PIK3CA p.E545A Reference Standard
詳細內容
CBP10543
Format
Genomic DNA
Description
PIK3CA E545G is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545G confers a gain of function on the Pik3ca protein as demonstrated by increased phosphorylation of Akt and transformation in cell culture (PMID: 17376864, PMID: 29533785).
Technical Data
DNA Change:
c.1634A>G
AA Change
p.E545G
Mutation type
Substitution - Missense
Zygosity
Heterozygous
Allelic Frequency
50%
Transcript
NM_006218
Cosmic ID
COSM764
Chr position(GRCh37)
chr3:178936092
Buffer:
Tris-EDTA
Product Information
Intended Use
Research Use Only
Unit Size
1ug
Concentration
Download for COA
Purity
Download for COA
DNA electrophoresis
Download for COA
Sanger sequencing
Download for COA
Storage
4℃
Expiry
36 months from the date of manufacture
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