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| CBP10197 | |
| Format | Genomic DNA |
| Description | TP53 L194F lies within the DNA binding domain of the Tp53 protein (UniProt.org). L194F results in decreased Tp53 transactivation activity and decreased binding to Bcl2 in cell culture (PMID: 16443602). |
| | |
| Technical Data |
| DNA Change | c.580C>T |
| AA Change | p.L194F |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM10995 |
| Chr position(GRCh37) | chr17:7578269 |
| Buffer | Tris-EDTA |
| | |
| Product Information |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
