| 名稱 | AI-Edigene® EGFR p.C797S 標準品 |
| 型號 | CBP10341 |
| 報價 |  |
| 特點 | AI-Edigene® EGFR p.C797S 標準品 |
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- 詳細內容
CBP10341 | |
| Format | Genomic DNA |
| Description | EGFR C797S lies within the ATP-binding pocket in the protein kinase domain of the Egfr protein (PMID: 25964297). C797S has been demonstrated to confer resistance to third-generation EGFR inhibitors (PMID: 25964297, PMID: 25948633, PMID: 29410323), but has not been biochemically characterized and therefore, its effect on Egfr protein function is unknown (PubMed, Jun 2018). |
| Technical Data | |
| DNA Change: | c.2389T>A |
| AA Change | p.C797S |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | ENST00000275493 |
| Chr position(GRCh37) | COSM6493937 |
| Chr position(GRCh37) | chr7:55249091 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1µg |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
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| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
